Xiaoling Hu

Postdoctoral Research Fellow
Laboratories for Computational Neuroimaging (LCN)
Athinoula A. Martinos Center for Biomedical Imaging
MGH/Harvard Medical School
Research Statement / CV / Linkedin / Twitter / Scholar / Github

I am currently a Postdoctoral Research Fellow at MGH/Harvard Medical School, hosted by Prof. Juan Eugenio Iglesias and Prof. Bruce Fischl.

I obtained my PhD degree from the Department of Computer Science at Stony Brook University, advised by Prof. Chao Chen. During my PhD, I have also been fortunate to spend time at United Imaging Intelligence (UII) and Allen Institute for Cell Science to explore various biomedical scenarios/applications.

Before that, I obtained my master and bachelor degrees from Tsinghua University and Huazhong University of Science and Technology, respectively.

Research Interests: My research interest is Medical AI, and I am focusing on developing core AI/ML algorithms applied to medical imaging problems. In particular, I am interested in:

  1. Topology-Driven Deep Image Analysis [NeurIPS'19, ICLR'21, MICCAI'21, ICLR'22, ECCV'22, NeurIPS'22, ICLR'23b, NeurIPS'23, ECCV'24a, MICCAI'24Wa]
  2. Uncertainty Estimation and Its Applications [ICLR'23a, ICLR'23b, ICCV'23b, NeurIPS'23]
  3. Learning with Imperfect Data [ICLR'23a, ICCV'23a, ICCV'23b, ECCV'24a, MedIA'24]
  4. Biomedical Applications [ECCV'22, ICCV'23a, ECCV'24b, MICCAI'24Wa, MICCAI'24Wb, MedIA'24, MICCAI'24a, MICCAI'24b, MICCAI'24c]
Email Address: xihu3 at mgh dot harvard dot edu

Contact Address: 149 13th St, Charlestown, MA 02129

Mentoring

  • Jiaqi Yang (Ph.D. student at Department of CS, CUNY)
  • Chen Li (Ph.D. student at Department of BMI, Stony Brook University)
  • Meilong Xu (Ph.D. student at Department of CS, Stony Brook University)
  • Wentao Huang (Ph.D. student at Department of CS, Stony Brook University)
  • Organized Tutorials/Workshops

    The First Workshop on Topology- and Graph-Informed Imaging Informatics (TGI3)
    Chao Chen, Bjoern Menze, Yash Singh, Xiaoling Hu, Johannes C. Paetzold, Saumya Gupta, Colleen Farrelly, Quincy Hathaway, Rahul Paul, Paul Rosen, Jennifer Rozenblit
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024
    Website

    Topology-Driven Image Analysis
    Chao Chen, Bjoern Menze, Xiaoling Hu, Johannes C. Paetzold, Saumya Gupta
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2023
    Website

    Selected Publications (Full Publications)

    (* denotes equal contributions, denotes students working closely with me)

    Publications

    TopoSemiSeg: Enforcing Topological Consistency for Semi-Supervised Segmentation of Histopathology Images
    Meilong Xu, Xiaoling Hu, Saumya Gupta, Shahira Abousamra, Chao Chen
    European Conference on Computer Vision (ECCV), 2024
    Paper Code

    Brain-ID: Learning Robust Feature Representations for Brain Imaging
    Peirong Liu, Oula Puonti, Xiaoling Hu, Daniel C. Alexander, Juan Eugenio Iglesias
    European Conference on Computer Vision (ECCV), 2024
    Paper Code

    Registration by Regression (RbR): a framework for interpretable and flexible atlas registration
    Karthik Gopinath*, Xiaoling Hu*, Malte Hoffmann, Oula Puonti, Juan Eugenio Iglesias
    Workshop on Biomedical Image Registration-MICCAI, 2024
    Paper

    P-Count: Persistence-based Counting of White Matter Hyperintensities in Brain MRI
    Xiaoling Hu, Annabel Sorby-Adams, Frederik Barkhof, W Taylor Kimberly, Oula Puonti, Juan Eugenio Iglesias
    Workshop on Topology- and Graph-Informed Imaging Informatics-MICCAI 2024
    Paper

    Spatial Diffusion for Cell Layout Generation
    Chen Li, Xiaoling Hu, Shahira Abousamra, Meilong Xu, Chao Chen
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024

    Hard Negative Sample Mining for Whole Slide Image Classification
    Wentao Huang, Xiaoling Hu, Shahira Abousamra, Prateek Prasanna, Chao Chen
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024

    Semi-Supervised Contrastive VAE for Disentanglement of Digital Pathology Images
    Mahmudul Hasan, Xiaoling Hu, Shahira Abousamra, Prateek Prasanna, Joel Saltz, Chao Chen
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2024

    Anomaly-guided weakly supervised lesion segmentation on retinal OCT images
    Jiaqi Yang, Nitish Mehtac, Gozde Demirci, Xiaoling Hu, Meera S. Ramakrishnan, Mina Naguib, Chao Chen, Chia-Ling Tsai
    Medical Image Analysis (MedIA), 2024
    Paper

    Topology-Aware Uncertainty for Image Segmentation
    Saumya Gupta, Yikai Zhang, Xiaoling Hu, Prateek Prasanna, Chao Chen
    Thirty-seventh Conference on Neural Information Processing Systems (NeurIPS), 2023
    Short version is also presented at NeurReps Workshop
    Paper Code Poster

    Calibrating Uncertainty for Semi-Supervised Crowd Counting
    Chen Li, Xiaoling Hu, Shahira Abousamra, Chao Chen
    International Conference on Computer Vision (ICCV), 2023
    Paper Code Slide Poster Video

    Enhancing Modality-Agnostic Representations via Meta-Learning for Brain Tumor Segmentation
    Aishik Konwer, Xiaoling Hu, Xuan Xu, Joseph Bae, Chao Chen, Prateek Prasanna
    International Conference on Computer Vision (ICCV), 2023
    Paper Slide

    Learning Probabilistic Topological Representations Using Discrete Morse Theory
    Xiaoling Hu, Dimitris Samaras, Chao Chen
    International Conference on Learning Representations (ICLR), 2023 (Spotlight, notable-top-25%)
    Short version is selected as Oral presentation at Medical Imaging meets NeurIPS Workshop
    Paper OpenReview Code Slide Poster

    Confidence Estimation Using Unlabeled Data
    Chen Li, Xiaoling Hu, Chao Chen
    International Conference on Learning Representations (ICLR), 2023
    Paper OpenReview Code Slide Poster

    Structure-Aware Image Segmentation with Homotopy Warping
    Xiaoling Hu
    Thirty-sixth Conference on Neural Information Processing Systems (NeurIPS), 2022
    Paper OpenReview Code Slide Poster

    Learning Topological Interactions for Multi-Class Medical Image Segmentation
    Saumya Gupta*, Xiaoling Hu*, ..., Prateek Prasanna, Chao Chen
    European Conference on Computer Vision (ECCV), 2022 (Oral, acceptance rate 2.7%)
    Paper Code Slide Poster Video

    Trigger Hunting with a Topological Prior for Trojan Detection
    Xiaoling Hu, Xiao Lin, Michael Cogswell, Yi Yao, Susmit Jha, Chao Chen
    International Conference on Learning Representations (ICLR), 2022
    Paper OpenReview Code Slide Poster

    A Topology-Attention ConvLSTM Network and Its Application to EM Images
    Jiaqi Yang*, Xiaoling Hu*, Chao Chen, Chia-Ling Tsai
    International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2021
    Paper OpenReview Code Slide Poster

    Topology-aware Segmentation Using Discrete Morse Theory
    Xiaoling Hu, Yusu Wang, Li Fuxin, Dimitris Samaras, Chao Chen
    International Conference on Learning Representations (ICLR), 2021 (Spotlight, acceptance rate 5.6%)
    Paper OpenReview Code Slide Poster

    Topology-Preserving Deep Image Segmentation
    Xiaoling Hu, Li Fuxin, Dimitris Samaras, Chao Chen
    Thirty-third Conference on Neural Information Processing Systems (NeurIPS), 2019
    Paper Code1 Code2 Slide Poster

    Thesis

    Learning Topological Representations for Deep Image Understanding
    Xiaoling Hu
    PhD Dissertation
    pdf ProQuest Slide

    Awards

    Catacosinos Fellowship, 2023

    Industry Experience


    Allen Institute (May 2022-Aug. 2022)
    Topology-Aware Image Segmentation

    United Imaging Intelligence (UII) (May 2021-Aug. 2021)
    Deep Shape Model Based Network

    Tencent Youtu Lab (June 2017-Jan. 2018)
    Object Detection and Clothes Search

    Services

    Reviewer for ICML, ICLR, NeurIPS, CVPR, ICCV, ECCV, AISTATS, MICCAI, AAAI etc.

    Reading Group

    Topology Data Analysis Reading Group